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KMID : 0032220090210020185
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Annals of Dermatology
2009 Volume.21 No. 2 p.185 ~ p.188
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Progression from Acral Lentiginous Melanoma in situ to Invasive Acral Lentiginous Melanoma
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Bae Jung-Min
Kim Hyung-Ok
Park Young-Min
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Abstract
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Acral lentiginous melanoma (ALM) is the most common type of cutaneous melanoma in Asians. The very early stage of ALM demonstrates only a proliferation of a few atypical melanocytes within the epidermis, and has been termed ALM in situ. A 74-year-old male patient presented with a pigmented lesion on the left great toe for 12 years, which had initially showed only a few scattered hyperplastic atypical melanocytes without dermal invasion upon biopsy 5 years ago. This time however, rebiopsy of the lesion confirmed a diagnosis of ALM, stage IIIB. It could be inferred that the lesion had slowly progressed from ALM in situ to invasive ALM over a period of 12 years. Herein we report a case of ALM in situ which progressed to invasive ALM over a long period of time. We expect this report may assist physicians in early recognition and proper management of future cases of ALM in situ.
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KEYWORD
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Acral Lentiginous melanoma in situ
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